The second half saw David Silva make his home debut, coming on for Isak shortly after the hour, while Casemiro, Fede Valverde and youngster Marvin Park, making his Madrid debut, came on for Zidane's side with 20 minutes left to play.
Barca make their debut at Sunday's big game when they entertain an impressive looking Villarreal, and their strike trio of Paco Alcacer, Gerard Moreno and Take Kubo. All eyes will be on Ronald Koeman's league debut in charge of a side that no longer contains players such as Luis Suarez, Arturo Vidal or Ivan Rakitic.
The remaining eight teams of the league will form the other group, to be based in Dalian, to fight off relegation, with the last to be relegated and the second to last will vie for a birth for the next CSL season with the winner of the second-tier league. Enditem
Jean Mota scored the winner eight minutes from time as Santos clinched their third win from four matches.
The 30-year-old title favorite Roglic, however, had to finished second, 59 seconds behind, after having worn the yellow jersey for 13 days, while Australia's Richie Porte, 35, took the third place on the podium.
Instead, goals were scored at the other end of the pitch, as Lucas Tousart's foul on Sebastian Rode allowed Daichi Kamada to curl the subsequent free-kick into the path of Bas Dost, who nodded home from close range in the 36th minute.
However, the 25-year-old Kipruto will be competing in an unfamiliar event in Doha, when he takes on compatriot Brimin Kipruto, Vincent Kibet and Bethwell Birgen in the men's 1,500m event.
‘I also hope very much that I can become one of the Winter Olympic volunteers, so that I can contribute my own modest strength to my country.’
Saturday ends with a difficult test for Real Madrid as they visit a Betis side under the guidance of former Madrid coach Manuel Pellegrini.
Potential successors for Wagner don't seem to be queuing up at the outfit's headquarters, but there may well be a new coach installed if the run of defeats continues.
The second half saw Wolves take the game to Manchester City, with Adama Traore looking for space behind their back line and the home side got back into the game with 12 minutes left to play when Raul Jimenez headed home an excellent cross from close range.